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April 12, 2012

London Olympics: A Biological Ground Zero?

The 2012 Olympics in London are at risk of becoming the next pandemic ground zero according to research conducted by Maplecroft.

The bad news is that London is only part of the story.
Singapore, North and South Korea, Italy, Germany, Netherlands, Belgium, France, and Spain make the extreme risk of pandemic list, too. None of them are hosting an Olympics, yet are on the same list with the same extreme risk ranking. Confusing? No so much.

Many of the countries noted by Maplesoft are at risk of flu spread as a result of environmental and living conditions. South East Asia is noted in the report as being "a particular risk of emerging strains of influenza" and China is noted as a particular concern. This should not be a surprise. We've been following the development of widely publicized diseases like Avian Flu from these areas for several years. What's different is our level of awareness today. We recognize that global events that bring so many people together from diverse locations brings with it increased disease spread potential.

What makes the 2012 Olympics in London different?
Nothing. In fact, the risk of disease transmission is not unique to  the London Olympic Games in any way. We would be having this same conversation if the Games were being held in Lake Placid, NY or Beijing, China. Mass gatherings have the potential to spread disease, influenza or otherwise. We discuss influenza most often because of the attention drawn to influenza A - H1N1/Swine Flu and H5N1/Highly Pathological Avian Influenza. Although they top the list of notable flu viruses, it's important to remember there are many other diseases of concern. These diseases hold threat potential regardless of the location of the event. The fact is simply highlighted because of the diverse population and environments the athletes and spectators will be coming from. Immune system status, comorbid conditions, and overall state of health of attendees will also be factors in the spread of disease. People will bring diseases as diverse as the culture and health environment they come from...and they'll take other diseases home with them, too. We should also consider the fact that the Olympic Games will be a high-profile event that may be an attractive target for a variety of threats including the biological bomber. Read more: YOU, the biological bomber

What may be different today is our awareness and sensitivity to the biological threat. 
Naturally occurring or intentionally released, a biological agent can be an extraordinarily deadly situation. Perhaps worse than a nuclear detonation, without the big bang, if you will. The good news is that, when compared to other threats, the biological event may be able to be contained and person-to-person transmission limited by simply washing your hands and wearing a mask. The non-pharmacological interventions go a long way to slow the spread of disease and support vaccination efforts. Read more on non-pharmacological interventions.

Technology is a new ally in disease tracking. As described in this video clip from Reuters, public health officials from all over the world are working to improve disease tracking before, during, and after the London Games.

How will the media respond to athletes and attendees at the London Games wearing masks?
This would not be the first time the issue has come up. The United States Cylcling team came under scrutiny for wearing face masks during the 2008 Olympic Games in Beijing. Pollution and air quality prompted the athletes to don the masks and subsequently sparked political issues between China and the U.S. Masks for pollution is one issue. Donning masks to prevent the spread of disease is quite another. Consider the global impact if we were to hear of a "flu-like" illness spreading through London and, at the same time, see athletes wearing N95 masks. It wouldn't take long for the speculation of an outbreak to be spun into the next pandemic.

Preparedness, of course.
There is another side to the threat...preparedness. The widely cited Maplecroft report clearly describes the 10 nations most at risk for pandemic influenza. What is less often noted is that this same report ranks an areas ability to contain a disease. This same research concluded that the U.K. is one of the countries most likely to be able to contain an outbreak:
"...the UK’s strong governance, highly developed infrastructure, well educated population and advanced health system also places it among the 10 countries with the highest capacity to contain a potentially lethal outbreak of a strain of flu." - quoted from Maplecroft.com
What's less clear is the preparedness in other countries. Attendees and athletes will return home with whatever (if anything at all) they've been exposed to. While strong infrastructure adds to resiliency, the lack of that infrastructure will add to disease complication and management. Read more on flu and biological preparedness.


October 11, 2011

BioAgent Facts app lacks virulence

BioAgent Facts app image UPMC
Facts, yes...pizazz, no.

BioAgent Facts app from the University of Pittsburgh Medical Center (UPMC) provides facts about diseases that could be encountered as a result of a naturally occurring event or intentional release. UPMC hosts the Center for Biosecurity and publishes several on-line publications such as Biosecurity News Today and Clinicians' Biosecurity News. I'm a subscriber to the UPMC/Biosecurity newsletter and familiar with their content quality.

Below is the text description of the BioAgent Facts app as given in the iTunes Store:
BioAgent Facts gives you facts about pathogens that could cause serious disease resulting from a natural epidemic or use as a biological weapon. This new app is offered by the Center for Biosecurity of the University of Pittsburgh Medical Center (UPMC) for those interested in learning more about these important diseases and the threat of bioterrorism. iTunes description
Overview:

BioAgent Facts screenshot (UPMC/iTunes)
BioSecurity Facts are listed for each pathogen convered. The pathogens covered in this release are:
  • Anthrax
  • Botulism
  • Flu
  • Plague
  • SARS
  • Smallpox
  • Tularemia
  • Viral Hemorrhagic Fevers (VHF)
  • and...Zombies? (Yes, Zombies)

Facts for each pathogen are categorized by tabs for:
  1. Background
  2. Illness
  3. Treatment
Background information includes further details on transmission and potential for use as a bioweapon.

Background screen (iTunes/UPMC)
Under the illness tab the user will find general signs and symptoms for each pathogen and variations. As with Anthrax and Plague, for example, the various types have their own subcategories.

The treatment tab includes information on prophylaxis, vaccine, as well as decontamination and personal protection as appropriate for each pathogen. BioAgent Facts app users are reminded to contact local health departments for more information during a confirmed biological attack and encouraged to report to your local hospital if you think you've been exposed, or exhibit unusual signs or symptoms.

Generally speaking, information in this app is well defined and the content written for those of us without advanced microbiology degrees. The source (UPMC) is a trusted authority and the facts are consistant with other sources including the Centers for Disease Control and Preventions Bioterrorism Agents/Diseases page.

The graphics and color choices used in the BioAgent Facts app are appealing, albeit somewhat spooky. The app is rated 9+ by iTunes for Infrequent/Mild Horror/Fear Themes. (Click here learn more about iTunes ratings) While the graphics/color scheme are engaging, I found the white text on blue background difficult to read. Use of the app was complicated by the inability to re-size the screen with gestures and small text.

Although the pathogens included in this release are potential threats, Dengue Fever and West Nile Virus may be timely additions. The "special feature" on Zombies is a complete waste of valuable real estate in this app. With all respect to popular culture, including zombies in BioAgent Facts diminishes the value and credibility of the app. The section dedicated to Zombies would be better served by including details of personal protective equipment such as N95 masks, guidelines for hand hygiene, respiratory etiquette, and appropriate social distancing during a biologic event. A segment on the importance/risks/benefits of vaccines would be more appropriate use of space as well.

BioAgent Facts is compatable with iPhone, iPod touch, and iPad with iOS 4.2 or later. I'm running this app on an iPhone4 with iOS 4.2. Its stable and runs quickly. The link for BioAgent Facts Support on iTunes links back to the UPMC homepage where the BioAgent Facts app icon has you running in circles back to iTunes. There is no mention of versions, additional features or anticipated upgrades.

Final Score:
Content: 2.0 I'd like to see more detail and better use of information. Telling people to report to your local hospital may not be the ideal action to take in every biologic situation and contacting the local health department may be impossible. The inclusion of a Zombie category lowers credibility, too. Dumping the Zombies and adding personal protection information or vaccine facts, and provide links for information rather than reporting to hospital or contact health department makes this a 4.0 app! I would not recommend this version BioAgent Facts for anything more than casual use.

Aesthetics/graphics: 4.0 I liked the graphics and color combinations.

Ease of Use: 2.0 I found the tabs/buttons too small and kept hitting the info button when trying to tap the home tab. Text is too small and white text on blue background was hard to read. Although stable on an iPhone (iOS 4.2) there is no clear support/FAQ available.

August 14, 2010

MJ Podcast #182: The Problem with PODs, Flu Season Preparation, and Prescription Medication Abuse.


I received a number of emails this week about a comment made on edition 181 of Mitigation Journal podcast...I was talking about my support for the United States Postal Service pharmaceutical delivery program the lack of functionality and failure potential of points of distribution. Leading off edition 182 is a discussion A few listeners/readers wanted to know why...nobody disagreed with me...just wanted more information on my opinion. One podcast listener actually wants me to write an opinion for their superiors and deliver some training on the topic of comprehensive biological event planning.

Matt and I also discuss the need to revisit flu season planning. Who knows what we're in for this flu season, but this is a good time to develop (or encourage) those good non-pharm infection control practices; respiratory etiquette, hand hygiene, and appropriate social distancing. Its also a good time to revisit your services infection control plan...review, update, train on it.  This segment of the podcast expands on several recent blog postings. For more on these topics check out these postings in Mitigation Journal blog CDC: Vaccine not a requirement, Forward Thinking for Flu  , and CDC Drops N95 Requirement

And finally this week, we talk about the importance of a medication profile and history in the pre-hospital environment. Medications and medication history are important but never so important as they are today. Prescription medication abuse is increasing faster than meth use and the rate of emergency calls due to abuse is rising. EMS responders must add medications and medication history to the list of things-to-do. I also encourage everyone to have a field guide that lists medications, indications, and side effects. I recommend the EMS Field Guide and Field Guide app for iPod/iPhoneTouch from Informed Publishing.

August 11, 2010

Forward Thinking for Flu

 It's that time of year again. Time to be forward thinking for flu.

As we approach another flu season it remains unclear what, if any, role H1N1 Swine Flu will play. Will there be another Type A influenza strain that will impact us? Will we see Swine Flu back as a seasonal visitor? Or, will we simply continue to have the various seasonal flu wax and wain throughout the season? I'm safe to say I don't know, nor will predict. Equally safe is the bet that nobody knows for sure.

Despite the less-than-glamorous remarks I get from some planners and responders, I continue to hold the position that flu; seasonal or novel strain, is a naturally occurring biological event. Look at the situation in that frame for just a second or two...If you knew there was going to be a biological event occurring in your community in the next few months, would you begin preparing for it now? I certainly hope so.

We know that seasonal influenza kills 30-35 thousand people in the United States every year. And we also know (now) that vaccine production and distribution in the event of a novel (or, perhaps intentional) biological event will be slow and sparse. So why wait until flu season (with or with a novel strain or variant) to begin preparing to meet the demands this naturally occurring event will place on your public and your service? I'd like to offer my list of things to consider when reviewing/planning for the 2010 flu season:

First, start or renew your infection control practices now. Get in (or back in) the habit of disinfecting your apparatus at the beginning of each tour, after each patient, and at the end of each tour. This includes wiping down all surfaces in the patient care compartment of ambulances, equipment that comes in contact with patients, and the cab of the vehicle. Don't neglect the place were you ride! Wipe down or disinfect the cab...with special attention to door handles, radio microphones, and the steering wheel.

 Second, although vaccination is still a great way to protect yourself from getting the flu, non pharmacutical interventions go a long way in stopping the spread of any disease. Remember to follow good hand hygiene practices by washing your hands as often as possible and using waterless sanitizers when soap and water are not available. Practice respiratory ettiquette - cover your cough and sneeze. Do so by coughing or sneezing into your elbow reduces the spray of material that comes out of you and into society. Also, wear a mask and don't be afraid to put a mask on your patient. The Centers for Disease Prevention and Control has recently dropped their requierment for N95 masks in the setting of flu in favor of surgical masks (See my previous Mitigation Journal post CDC Drops N95 Requirement) Also, consider appropriate social distancing...that is, stay home if you're sick. Many employers don't like to hear about this one. It is irresponsible to go to work (especially if you have contact with the public) if you are ill. Those involved in planning must account for the possibility that the workforce will be decreased, perhaps significantly, by members not reporting due to illness. You must also consider the absentee rate to increase due to employees remaining home to care for significant others who are ill or children when schools/daycare centers are closed. 

I encourage everyone to review the Mitigation Journal posting Bio-Event Ready or Die! 3 Thing to do, Today. originally posted August, 2009, for more on this topic.


For a summary of Mitigation Journal blog postings and podcast episodes on flu and flu-related topics, click here

August 6, 2010

CDC Drops N95 Requirement

CDC Drops N95 Requirement...and boy, do I feel good about it! 

N95 - Surgical Mask Just as Good
I've been arguing that the Centers for Disease Control and Prevention (CDC) requirement for N95's was not only expensive but, cumbersome, and difficult to ensure compliance. Pushing my  thoughts on the use of surgical masks over N95's has caused me significant headache...from the 2003 SARS epidemic to 2009 Swine Flu. I've written my opinion of surgical masks over N95 and stood by it for years.  See Bio-Event Ready or Die! 3 Thing to do, Today. originally published August, 2009 and On The Topic of N95s originally published May, 2009.
 .
But now, the CDC has issued opinion that surgical masks can be used in place of the N95.

I've been outspoken in classes; and now, it seems that the CDC agrees with me! The recent document from the CDC Interim Guidance for the Use of Masks to Control Influenza Transmission states the following:

About time they listened to me
"The use of surgical or procedure masks by infectious patients may help contain their respiratory secretions and limit exposure to others. Likewise, when a patient is not wearing a mask, as when in an isolation room, having health-care personnel mask for close contact with the patient may prevent nose and mouth contact with respiratory droplets. However, no studies have definitively shown that mask use by either infectious patients or health-care personnel prevents influenza transmission. In the United States, disposable surgical and procedure masks have been used widely in health-care settings to prevent exposure to respiratory infections, but they have not been used commonly in community settings (e.g., schools, businesses, public gatherings)."
 and further states -
"A surgical or procedure mask should be worn by health-care personnel who are in close contact (i.e., within 3 feet) with a patient who has symptoms of a respiratory infection, particularly if fever is present, as recommended for standard and droplet precautions. "

August 6, 2009

Bio-Event Ready or Die!

     ...or at least get sick. 3 Things to do today to prevent even that!

Biological events can be natural or intentional. The intentional kind is what you'll learn about in a weapons of mass destruction (WMD) training class and you read about in the papers. The naturally occurring kind...SARS or pandemic influenza, for example...are the kind that go on almost every year and we don't pay much attention to. One is intentional, one is natural. Both can be deadly, both have lessons to be learned. We've seen both types in the last ten years; SARS and West Nile Virus...naturally occurring, Anthrax, intentional. Again, both situations with lessons to teach. But did we learn anything?

Here we are in 2009 and many documents and memos are urging us to "get ready" for pandemic flu, H1N1 or otherwise. SARS hit the world back in 2003...what did we learn? It is way past time to be getting ready, we have to be ready. Its not as hard as you'd think and you don't need dozens of pages of plans, either.

Despite the intent, there are similarities between intentional and naturally occurring biological events that we can use to our preparedness advantage. Even the traditional WMD training can be translated to natural event readiness. Unfortunately, most of the WMD training has been a waste of time and preparedness dollars spent on big, shinny things and security cameras.

Traditional responders and the health care system is marginally better prepared today than it was on September 10, 2001. After Anthrax, after SARS.

Recently, the Centers for Disease Control and Prevention (CDC) has predicted that 40% of the United States population will become sick with 2009 H1N1 Swine Flu. That's 40% of the average population. Not to mention those in health care, emergency response, and those with risk factors. And considering the disease as it is today...not accounting for any antigenic drift. Keep in mind H5N1 or Avian Flu continues to lurk and there has been a strain of H3N2 found to be undergoing change.

By way of review, the H's and N's stand for proteins on the influenza type A virus. There are several types H's and N's that, in combination add up to tricky business for vaccine procedures. Influenza vaccine has to match the H and N combination. If not, the vaccine is not effective.

My top three things to do to Be Ready for a natural or intentional biological event:
  1. Train your people on infection control and personal protective equipment (PPE) more than once a year. This is the time to develop good habits for regular cleaning and disinfection of our vehicles. Also, several studies have pointed to practice with masks...getting proper fit and know how to put them on properly...as being more important than annual fit-testing. By the way, numerous sources have also indicated that the N95 mask may be no better standard surgical masks for protection against viruses.
  2. Promote the safety and health of responders and their families. That means getting appropriate vaccine or other medications available for your personnel and at-risk family. Identify those who can't get vaccinated or take medications and take steps to isolate them from infection. Numerous self-report surveys have concluded that one key to keeping your personnel coming to work in a biological event is provide for the safely of the family.
  3. Prepare a Can't Go Home Plan. Stock you stations and facilities with food, water, hygiene products and ready additional bunk areas to keep personnel in-house during extended operational periods.
As always, I look forward to comment and debate. If you have something you'd like to add to the list...email me at mitigationjournal@gmail.com

December 27, 2006

These providers saved lives…at risk of their own.

The Chicago Sun-Times reported that five paramedics and one paramedic student were overcome by chemical fumes after responding to what they thought was an asthma attack.

As reported in the Sun-Times; a man had been attempting to open a clogged household drain for several days using a variety of “consumer-level hazardous materials” (consumer-level hazardous materials or CLHM, is my phrase for the chemical products available at grocery stores, drug stores, Home Depot, Lowes…ect. that if used property are no big deal, but used improperly or mixed create a hazard..)

It seems that the homeowner died from the fumes emitted by mixing several consumer-level hazardous materials; Liquid-Plumr, chlorine bleach, and Rooto. The Liquid-Plumr was used first and after several days – he started adding the other products – resulting in the “consumer-level hazardous materials event. (A Consumer-Level Haz Mat would be an event created by improper use or mixing of this type of chemical and typically found in the single or multi-occupant residential setting or resident/institutional setting…a nursing home or school dorm.)

EMS was dispatched for an asthma attack and found the homeowner dead, his wife and adult son overcome and incapacitated. The paramedics rescued the victims from the house…becoming exposed to the fumes and requiring hospitalization. The article states that “The paramedics didn’t wear masks when they went in because they thought they were there for an asthma attack.”

Some important issues for discussion:
“Consumer-Level Hazardous Materials” or CLHMs contain a legitimate danger even if used properly. You should note that Liquid-Plumr contains Sodium Hypochlorite (NaClo = sodium hydroxide + Chlorine, A.K.A. bleach) and Lye as a stabilizer. Lye is also known as caustic soda and causes defatting/sapofacation…liquefaction of the tissues. This is considered worse than an acid burn and from what I can read, the other products (Commet and Rooto) contain sulphuric acid (H2SO4)

When you mix this stuff together, you’re going to get nasty results. In general, BLEACH + Acid yields CHLORINE GAS, BLEACH + AMMONIA yield Chloramines. This reaction can be violent, especially if the reaction takes place in a confined container or builds pressure as chlorine gas and oxygen are liberated.

These chemicals can (and are) used to create Homemade Chemical Bombs or HCB’s. For more on HCB’s see Homemade Chemical Bombs: A Legitimate Threat to Responders, Mitigation Journal (August 2006) Link: http://mitigationjournal.blogspot.com/2006/08/homemade-chemical-bombs-legitimate.html

It is reasonable to assume that this EMS service did not carry SCBA and therefore, any masks they could have used would be of the infection control type. HEPA masks, N95 masks and the like will provide no protection from chemical exposure. None whatsoever, remember that. The best you may be able to do is identify the situation and call for appropriate resources.

This scenario once again proves my point for the all-hazards approach to planning and training. This was not a terrorist event yet, the dangers are similar as are the ancillary concerns of responder safety, decontamination, receiving at the hospital, multi-agency integration (NIMS, anyone?) and mitigation.

Do yourself and your partners a favor; the next time you’re in the store, take a look at the chemicals in these consumer-level hazardous materials and do some simple research.

Read the Chicago Sun-Times article here:
http://www.suntimes.com/news/metro/179079,CST-NWS-orland20.article